Causal pathways in Lymphoma: The role of serum metabolites and immune cells determined by Mendelian randomization
The study establishes a causal connection between immune cells and lymphoma, partially mediated by serum metabolites, although the majority of the influence remains undefined. Future research should explore additional potential mediators. Clinically, there should be an increased focus on immune cells biomarkers for lymphoma patients. These results offer valuable insights for identifying lymphoma biomarkers and potential therapeutic targets.
Authors
- Yifen Shi (ORCID: https://orcid.org/0000-0003-2912-2856)
- Songfu Jiang
- Xia Zhang
- Xiaoying Man
- Xin Zhuang (ORCID: https://orcid.org/0009-0005-5885-0408)
- Ruochen Wang (ORCID: https://orcid.org/0000-0003-2338-5444)
- Rong Yang
- Hailin Wang (ORCID: https://orcid.org/0000-0002-1843-999X)
- Qingning Yin
Institutions
- Wenzhou Medical University (CN)
- First Affiliated Hospital of Wenzhou Medical University (CN)
- Qinghai No.3 People's Hospital (CN)
Publication Details
- Journal
- International Immunopharmacology
- Published
- 2024-11-25
- DOI
- https://doi.org/10.1016/j.intimp.2024.113593
- Citations
- 1
- Primary Topic
- Genetic Associations and Epidemiology
- Type
- article
- Field-Weighted Citation Impact
- 0.55