Prevalence and management of ICU delirium—Time to think outside the box

Delirium presents a significant management challenge in the intensive care unit (ICU) setting of various hospital systems and leads to significant morbidity and mortality. Significant portion of psychiatry consultation involves management of agitation associated with this condition. While it is acknowledged that a definitive consensus on the pharmacological management of delirium is lacking, resulting in notable frustration among care teams and families, this review aims to aggregate existing evidence and present a comprehensive overview of the current landscape and potential gaps in literature. This narrative review seeks to condense the disparate research and work done on the medical and non-medical management of delirium in the ICU.