Too Big to Fail

This is the largest reported single-center series of pediatric major hepatectomies. PHLF is exceedingly rare in children. The liver volume-to-BW ratio is higher in children compared with adults, and the FLR is sufficient even in extreme resections with <20% of the liver remnant. These findings strongly question the use of asociating liver partition and portal vein ligation for staged hepatectomy, portal vein embolization, or transplantation based on suspected insufficient liver remnants in children.

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Publication Details

Journal
Annals of Surgery
Published
2024-11-25
DOI
https://doi.org/10.1097/sla.0000000000006595
Citations
6
Primary Topic
Hepatocellular Carcinoma Treatment and Prognosis
Type
article
Field-Weighted Citation Impact
2.22
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article

Too Big to Fail

Juri Fuchs, Lucas Rabaux‐Eygasier, Florent Guérin, Thomas Husson et al.
6 citations
Annals of Surgery
Hepatocellular Carcinoma Treatment and Prognosis
2.22
article

Too Big to Fail

Juri Fuchs, Lucas Rabaux‐Eygasier, Florent Guérin, Thomas Husson, Virginie Fouquet, G. Héry, Sophie Branchereau
article en
6 citations

Abstract

This is the largest reported single-center series of pediatric major hepatectomies. PHLF is exceedingly rare in children. The liver volume-to-BW ratio is higher in children compared with adults, and the FLR is sufficient even in extreme resections with <20% of the liver remnant. These findings strongly question the use of asociating liver partition and portal vein ligation for staged hepatectomy, portal vein embolization, or transplantation based on suspected insufficient liver remnants in children.

Annals of SurgeryVol. 281(3)
Heidelberg University (DE), Université Paris-Saclay (FR), Assistance Publique – Hôpitaux de Paris (FR), Bicêtre Hospital (FR), Hôpital Paul-Brousse (FR)
Good health and well-being
Openalex Percentile: Top 11%
Hepatocellular Carcinoma Treatment and Prognosis
2.22
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Too Big to Fail — Juri Fuchs, Lucas Rabaux‐Eygasier, et al. · Annals of Surgery (2024) | TGRS Research Map | TGRS