Complex application of high-intensity phototechnologies in the treatment of diffuse alopecia

The purpose of the study. The issues of treatment of patients with diffuse alopecia are being actively investigated at the present time. Promising in this regard are laser technologies, including in combination with drugs, which determined the relevance of this study. The aim of the study was to scientifically substantiate and develop a combined method including fractional laser therapy, intravenous blood irradiation and minoxidil for the treatment of patients with diffuse telogenetic alopecia. Materials and methods. To study the effectiveness of laser technologies, 4 treatment regimens were analyzed. A total of 177 patients with an established diagnosis of diffuse telogenetic alopecia were under observation. To study the effectiveness and safety of the developed combined method, as well as its components, a visual hair loss scale (VSHVV) was used in the study. Results. The best result in patients with mild severity was obtained in the combination therapy group, where the dynamics was 36.9 %. While in the group using erbium and neodymium lasers, the dynamics was 25 %, in the group where percutaneous laser irradiation of blood was used –21.1 %, in the control group — 19.3 %. The best result in patients with severe severity was obtained in the combination therapy group, where the dynamics was 70.8 %. While in the group using erbium and neodymium lasers, the dynamics was 60.8 %, in the group using percutaneous laser irradiation of blood –57.7 %, in the control group 55.7 %. Conclusion. Thus, the developed method of combined therapy of patients with mild and severe diffuse alopecia is highly effective and can be recommended for use in a wide clinical practice.