Von Hippel-Lindau deficiency protects the liver against ischemia/reperfusion injury through the regulation of hypoxia-inducible factor 1α and 2α
Thus, we identified the VHL-HIF-1α/HIF-2α axis as an indispensable pathway that may be a novel target for mediating hepatic I/R injury.
Authors
- Miaoyu Bai (ORCID: https://orcid.org/0000-0002-0467-4710)
- Hongjun Yu (ORCID: https://orcid.org/0000-0001-6754-4801)
- Shounan Lu (ORCID: https://orcid.org/0000-0001-9569-3644)
- Yong Ma (ORCID: https://orcid.org/0000-0002-6508-508X)
- Shanjia Ke
- Yanan Xu (ORCID: https://orcid.org/0000-0003-3582-8863)
- Bing Yin (ORCID: https://orcid.org/0000-0001-8668-9504)
- Yongzhi Zhou
- Hongchi Jiang (ORCID: https://orcid.org/0000-0001-8215-8984)
- Zihao Li (ORCID: https://orcid.org/0000-0002-4040-8188)
- Chaoqun Wang (ORCID: https://orcid.org/0000-0001-9912-9477)
- Zhongyu Li (ORCID: https://orcid.org/0000-0001-8086-7461)
- Xinglong Li (ORCID: https://orcid.org/0000-0003-1656-7370)
- Baolin Qian
Institutions
- Army Medical University (CN)
- Harbin Medical University (CN)
- Dalian Medical University (CN)
- Peking University (CN)
- Second Affiliated Hospital of Chongqing Medical University (CN)
- Peking University People's Hospital (CN)
- Affiliated Hangzhou First People's Hospital, Westlake University, School of Medicine (CN)
- First Affiliated Hospital of Harbin Medical University (CN)
- Zhejiang University (CN)
- Chongqing Medical University (CN)
Publication Details
- Journal
- Hepatology Communications
- Published
- 2024-11-25
- DOI
- https://doi.org/10.1097/hc9.0000000000000567
- Primary Topic
- Cancer, Hypoxia, and Metabolism
- Type
- article
- Field-Weighted Citation Impact
- 0.00
Funders
- Harbin Medical University
- China Postdoctoral Science Foundation
- Natural Science Foundation of Heilongjiang Province