Pelvic Desmoplastic Small Round Cell Tumor on 18F-PSMA PET/CT

Desmoplastic small round cell tumor (DSRCT) as a subtype of sarcoma is rare and aggressive. We present the case of a 23-year-old man with a histologically confirmed DSRCT who underwent 18F-PSMA PET/CT before prostate biopsy and surgical resection of the tumor. It is well known that PSMA PET has a high accuracy for detecting clinically significant prostate adenocarcinoma and is useful in guiding prostate biopsy. This case signifies DSRCT can also exhibit intermediate PSMA expression on 18F-PSMA PET/CT.