Assessment of Home-based Monitoring in Adults with Chronic Lung Disease: An Official American Thoracic Society Research Statement
<b>Background:</b> There is increasing interest in the use of home-based monitoring in people with chronic lung diseases to improve access to care, support patient self-management, and facilitate the collection of information for clinical care and research. However, integration of home-based monitoring into clinical and research settings requires careful consideration of test performance and other attributes. There is no published guidance from professional respiratory societies to advance the science of home-based monitoring for chronic lung disease. <b>Methods:</b> An international multidisciplinary panel of 32 clinicians, researchers, patients, and caregivers developed a multidimensional framework for the evaluation of home-based monitoring in chronic lung disease developed through consensus using a modified Delphi survey. We also present an example of how the framework could be used to evaluate home-based monitoring using spirometry and pulse oximetry in adults with asthma, bronchiectasis/cystic fibrosis, chronic obstructive pulmonary disease, and interstitial lung disease. <b>Results:</b> The PANACEA framework includes seven domains (test Performance, disease mANAgement, Cost, patient Experience, clinician Experience, researcher Experience, and Access) to assess the degree to which home-based monitoring assessments meet the conditions for clinical and research use in chronic lung disease. Knowledge gaps and recommendations for future research of home spirometry and pulse oximetry in asthma, bronchiectasis/cystic fibrosis, chronic obstructive pulmonary disease, and interstitial lung disease were identified. <b>Conclusions:</b> The development of the PANACEA framework allows standardized evaluation of home-based monitoring in chronic lung diseases to support clinical application and future research.
Authors
- Michael Freedman (ORCID: https://orcid.org/0000-0002-5322-0571)
- Teresa Barnes (ORCID: https://orcid.org/0000-0002-1036-7311)
- Vitalii Poberezhets (ORCID: https://orcid.org/0000-0003-2581-824X)
- Ron Flewett
- Linzy Houchen-Wolloff (ORCID: https://orcid.org/0000-0003-4940-8835)
- Isabel Saraiva
- Maureen George (ORCID: https://orcid.org/0000-0001-9234-7842)
- Anne Elizabeth Holland (ORCID: https://orcid.org/0000-0003-2061-845X)
- Toni Gibson-Latimer (ORCID: https://orcid.org/0000-0001-8684-8624)
- Jeanette Boyd (ORCID: https://orcid.org/0009-0009-8636-8829)
- H. WINNETT ORR
- Vincent S. Fan (ORCID: https://orcid.org/0000-0002-6178-1117)
- Kerri I. Aronson (ORCID: https://orcid.org/0000-0001-5587-5427)
- Christopher J. Ryerson (ORCID: https://orcid.org/0000-0003-1049-393X)
- John Linnell (ORCID: https://orcid.org/0000-0002-7748-0423)
- Andrea Arlene Pappalardo (ORCID: https://orcid.org/0000-0002-4901-3465)
- Marlies Wijsenbeek (ORCID: https://orcid.org/0000-0002-4527-6962)
- Hilary Pinnock (ORCID: https://orcid.org/0000-0002-5976-8386)
- Rachel Alder
- Surinder Singh Birring (ORCID: https://orcid.org/0000-0003-2525-6291)
- Yet Hong Khor (ORCID: https://orcid.org/0000-0002-5434-9342)
- James Duncan Chalmers (ORCID: https://orcid.org/0000-0001-5514-7868)
- Russell G. Buhr (ORCID: https://orcid.org/0000-0001-6159-7435)
- Jerry A. Krishnan (ORCID: https://orcid.org/0000-0001-5525-4778)
- Karin Wadell (ORCID: https://orcid.org/0000-0001-7334-8698)
- Catharina C. Moor (ORCID: https://orcid.org/0000-0002-5295-2877)
- Hayoung Choi (ORCID: https://orcid.org/0000-0003-4812-0653)
- Henrik Watz
- Uma Maheswari Krishnaswamy (ORCID: https://orcid.org/0000-0002-5144-4731)
- Fernando J. Martinez (ORCID: https://orcid.org/0000-0002-2412-3182)
- Barbara Crossley
- Roberto Benzo
Institutions
- Mayo Clinic (US)
- University of British Columbia (CA)
- Hallym University (KR)
- University of California, Los Angeles (US)
- University of Dundee (GB)
- University of Washington (US)
- Cornell University (US)
- Hallym Polytechnic University (KR)
- British Lung Foundation (GB)
- Erasmus MC (NL)
- University Hospitals of Leicester NHS Trust (GB)
- University of Illinois Chicago (US)
- Institute for Breathing and Sleep (AU)
- St. John's National Academy of Health Sciences (IN)
- National Pirogov Memorial Medical University, Vinnytsya (UA)
- LungenClinic Grosshansdorf (DE)
- Alfred Health (AU)
- Austin Health (AU)
- Monash University (AU)
- Seattle University (US)
- Columbia University (US)
- Umeå University (SE)
- Erasmus University Rotterdam (NL)
- University of Edinburgh (GB)
Publication Details
- Journal
- American Journal of Respiratory and Critical Care Medicine
- Published
- 2024-11-25
- DOI
- https://doi.org/10.1164/rccm.202410-2080st
- Citations
- 13
- Primary Topic
- Chronic Obstructive Pulmonary Disease (COPD) Research
- Type
- article
- Field-Weighted Citation Impact
- 5.45
Funders
- U.S. Department of Veterans Affairs
- American Thoracic Society
- Scleroderma Foundation
- Bristol-Myers Squibb
- American Academy of Allergy Asthma and Immunology
- American Lung Association
- Pulmonary Fibrosis Foundation
- Stony Wold-Herbert Fund
- Eli Lilly and Company
- AstraZeneca
- GlaxoSmithKline
- Sanofi
- Illinois Department of Public Health
- Gilead Sciences
- Biogen
- Teva Pharmaceutical Industries
- Food Allergy Research and Education
- F. Hoffmann-La Roche
- Northwestern University
- Health Services Research and Development
- University of Washington
- Respiratory Health Association
- COPD Foundation
- CSL Behring
- European Respiratory Society
- Sunovion
- Regeneron Pharmaceuticals
- Austin Medical Research Foundation
- University Hospitals of Leicester NHS Trust
- Galecto
- Veracyte
- Horizon Therapeutics
- Insmed
- National Institute for Health and Care Research
- Asthma and Lung UK
- University of Cambridge
- University of Leicester
- University of Edinburgh
- University of Aberdeen
- Royal Australasian College of Physicians
- Thoracic Society of Australia and New Zealand
- Hallym University
- Cambridge University Hospitals
- Daiichi-Sankyo
- Lung Foundation Australia
- Deutsches Zentrum für Lungenforschung
- Lung Foundation Netherlands
- Grifols
- National Institutes of Health
- Agency for Healthcare Research and Quality
- Genentech
- Weill Cornell Medical College
- HORIZON EUROPE Framework Programme
- Medical Research Council
- National Health and Medical Research Council
- National Heart, Lung, and Blood Institute
- National Center for Advancing Translational Sciences
- National Institute on Minority Health and Health Disparities
- Daiichi Sankyo Europe