Isolation and analysis of residual leucocytes from leucoreduced red blood cell units

Viable CD45+/CD34+ cells were isolated from leucoreduced RBC units, indicating the potential for donor progenitor cells to be present during transfusion. Further characterization of these residual cells is required to explain how TAM may occur in some patients following RBC transfusion.

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Publication Details

Journal
Vox Sanguinis
Published
2024-11-25
DOI
https://doi.org/10.1111/vox.13775
Primary Topic
Erythrocyte Function and Pathophysiology
Type
article
Field-Weighted Citation Impact
0.00
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article

Isolation and analysis of residual leucocytes from leucoreduced red blood cell units

Rena Hirani, David O. Irving, Melinda M. Dean
Vox Sanguinis
Erythrocyte Function and Pathophysiology
article

Isolation and analysis of residual leucocytes from leucoreduced red blood cell units

Rena Hirani, David O. Irving, Melinda M. Dean
article en

Abstract

Viable CD45+/CD34+ cells were isolated from leucoreduced RBC units, indicating the potential for donor progenitor cells to be present during transfusion. Further characterization of these residual cells is required to explain how TAM may occur in some patients following RBC transfusion.

Vox SanguinisVol. 120(3)
University of Technology Sydney (AU), University of the Sunshine Coast (AU), Australian Red Cross Lifeblood (AU), Macquarie University (AU)
Openalex Percentile: Top 70%
Erythrocyte Function and Pathophysiology
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