Base‐Mediated Sequential Annulation Reaction of Conjugated Dienes and Crotonate‐Derived Sulfur Ylides: Effective Synthesis of Bicyclo[4.1.0]heptenes
Abstract Herein we present a method for base‐mediated sequential annulation reaction of conjugated dienes. The method offers an efficient pathway for the effective construction of bicyclo[4.1.0]heptenes. Notable features of this approach include good yields, remarkable stereoselectivity, as well as a broad substrate scope and significant step efficiency. In addition, the reaction could be effectively scaled up to a gram scale under standard condition.
Authors
- Jingran Sun
- Er‐Qing Li (ORCID: https://orcid.org/0000-0003-1286-6832)
- Zhenjie Gan
- Yue Wang (ORCID: https://orcid.org/0000-0001-6936-5081)
- Zhengqing Cai (ORCID: https://orcid.org/0009-0001-9920-7188)
- Z.‐T. HUANG (ORCID: https://orcid.org/0000-0001-5018-0829)
Institutions
- Hainan University (CN)
- Henan University of Technology (CN)
- Zhengzhou University (CN)
- Henan University of Engineering (CN)
Publication Details
- Journal
- Advanced Synthesis & Catalysis
- Published
- 2024-11-25
- DOI
- https://doi.org/10.1002/adsc.202401273
- Citations
- 4
- Primary Topic
- Cyclopropane Reaction Mechanisms
- Type
- article
- Field-Weighted Citation Impact
- 1.00