Distinguishing <i>ABCA4</i> from <i>PRPH2</i> -related disease: qualitative analysis of examination and imaging features
Peripapillary sparing and pisciform flecks are more highly associated with <i>ABCA4</i>-related disease, while macular chorioretinal atrophy is more highly associated with <i>PRPH2</i>-related disease. Logistic regression demonstrates that bull's eye maculopathy and macular flecks are predictive of the <i>ABCA4</i> genotype.
Authors
- Tim Becker (ORCID: https://orcid.org/0000-0002-6573-1109)
- Breck Nichols
- Roa Sadat (ORCID: https://orcid.org/0000-0002-3889-1414)
- Calvin W. Wong (ORCID: https://orcid.org/0000-0003-1847-0089)
- Kenneth C. Fan (ORCID: https://orcid.org/0000-0002-4453-9337)
- David M. Brown
- Charles C. Wykoff
Institutions
- Methodist Hospital (US)
- Retina Consultants of Texas (US)
- Methodist Hospital (US)
- The University of Texas Health Science Center at Houston (US)
Publication Details
- Journal
- Ophthalmic Genetics
- Published
- 2024-11-25
- DOI
- https://doi.org/10.1080/13816810.2024.2432064
- Primary Topic
- Connective tissue disorders research
- Type
- article
- Field-Weighted Citation Impact
- 0.00