Mechanochemical activation of 2D MnPS3 for sub-attomolar sensing
Molecular detection is important in biosensing, food safety, and environmental surveillance. The high biocompatibility, superior mechanical stability, and low cost make plasmon-free surface-enhanced Raman scattering (SERS) a promising sensing technique, the ultrahigh sensitivity of which is urgently pursued for realistic applications. As a proof of concept, we report a mechanochemical strategy, which combines the wrinkling and chemical functionalization, to fabricate a plasmon-free SERS platform based on 2D MnPS<sub>3</sub> with a sub-attomolar detection limit. In detail, the formation of wrinkles in 2D MnPS<sub>3</sub> enables a SERS substrate of the material to detect trace methylene blue molecules. The mechanism is experimentally revealed that the wrinkled structures contribute to the improvement of light-matter coupling. On this basis, decorating a wrinkled MnPS<sub>3</sub> which has absorbed methylene blue with histamine dihydrochloride further lowers the detection limit to 10<sup>-19</sup> M. Because the amino groups in histamine dihydrochloride molecules are crosslinkers that create more pathways to promote charge transfer between these substances. This work provides a guidance for the design of SERS sensors with single-molecule-level sensitivity.
Authors
- Xin‐An Zeng (ORCID: https://orcid.org/0000-0002-8792-2336)
- Changjiu Teng (ORCID: https://orcid.org/0000-0001-8712-3019)
- Shilong Zhao (ORCID: https://orcid.org/0000-0001-9491-4337)
- Baofu Ding (ORCID: https://orcid.org/0000-0001-6646-7285)
- Zhiqiang Lin (ORCID: https://orcid.org/0000-0003-1834-2060)
- Bilu Liu (ORCID: https://orcid.org/0000-0002-7274-5752)
- Wenjun Chen (ORCID: https://orcid.org/0000-0002-0002-3013)
- Hui–Ming Cheng (ORCID: https://orcid.org/0000-0002-5387-4241)
- Junhua Huang (ORCID: https://orcid.org/0000-0002-0092-396X)
- Benli Zhao
- Xuan Weng (ORCID: https://orcid.org/0000-0002-2215-4946)
- Junyang Tan
- J. Gui (ORCID: https://orcid.org/0009-0000-3963-1238)
- Lang‐Hong Wang
Institutions
- Foshan University (CN)
- Sun Yat-sen University (CN)
- Shenzhen Institute of Information Technology (CN)
- Chinese Academy of Sciences (CN)
- Tsinghua–Berkeley Shenzhen Institute (CN)
- Institute of Metal Research (CN)
- Stomatology Hospital (CN)
- Shenzhen Institutes of Advanced Technology (CN)
- Tsinghua University (CN)
Publication Details
- Journal
- Nature Communications
- Published
- 2024-11-25
- DOI
- https://doi.org/10.1038/s41467-024-54608-0
- Citations
- 8
- Primary Topic
- Polydiacetylene-based materials and applications
- Type
- article
- Field-Weighted Citation Impact
- 2.00
Funders
- National Natural Science Foundation of China
- National Science Fund for Distinguished Young Scholars
- Basic and Applied Basic Research Foundation of Guangdong Province
- Division of Materials Research
- Tsinghua Shenzhen International Graduate School