Relation Between Anemia and ABO Blood Group in Pregnant Women: Retrospective Observational Study in Tobruk, Libya

Anemia is one of the most common complications related to pregnancy. Normal physiologic changes in pregnancy affect the hemoglobin (Hb), and there is a relative or absolute reduction in Hb concentration. The purpose of this study was to evaluate the incidence of anemia among pregnant women and its relation to blood group and occurrence of anemia, so that preventive measures can be taken to combat anemia in women who are more susceptible to it. The retrospective study was conducted on 2469 pregnant who are in the age group of 18-45 years in Tobruk Medical Center. Blood samples were determined using tube method using antisera A, B and D and the Hemoglobin concentration analysis was estimated using Sysmex XP-300. In our study we found that women with blood group A+ and O+ (36%) were more prone for anemia, followed by B+ (20%), AB+ (7 %). Chi-square value exhibited 26.538 with a p-value of 0.143 which was showing non-significant (> 0.05) association between anemia and all blood groups. We can conclude that pregnant with blood groups A and O were more prone to anemia followed by blood group B and least with blood group AB. Additional research is required to determine the causes and related factors of anemia among pregnant women. The exact mechanisms behind the relationship between ABO blood group and anemia are not fully understood. However, it is hypothesized that the antibodies produced by different blood groups may interact with red blood cells in ways that impact their lifespan or production. Understanding this relationship is crucial for developing targeted interventions to manage anemia in pregnant women, ensuring better maternal and fetal health outcomes.