FSTL1 Can Be a Promising Target in TMJ Osteoarthritis via Regulating Chondrocyte Mitophagy and Apoptosis
To sum up, upregulated expression level of FSTL1 in synovial fluid promoted the progression of TMJ OA by upregulating accelerating the chondrocyte apoptosis and mitophagy, and suppressing the FSTL1 in TMJ can rescue the OA progression. Therefore, it may be a promising result to consider the FSTL1 as a therapeutic target in the future.
Authors
- Jiayao Wang (ORCID: https://orcid.org/0000-0003-2753-6000)
- Qian Wang (ORCID: https://orcid.org/0000-0003-4531-9499)
- Fangjie Li (ORCID: https://orcid.org/0000-0001-7683-3461)
- Minghua Gao
Institutions
- Huzhou Normal University (CN)
Publication Details
- Journal
- Journal of Craniofacial Surgery
- Published
- 2024-11-25
- DOI
- https://doi.org/10.1097/scs.0000000000010906
- Citations
- 1
- Primary Topic
- Osteoarthritis Treatment and Mechanisms
- Type
- article
- Field-Weighted Citation Impact
- 0.47