GDF15 propeptide promotes bone metastasis of castration-resistant prostate cancer by augmenting the bone microenvironment
GDPP augments the tumor microenvironment of BM and is a novel blood biomarker of BM in CRPC, which could lead to early treatment interventions in patients with CRPC.
Authors
- Kosuke Nakano (ORCID: https://orcid.org/0000-0001-5356-7359)
- Seiji Okada (ORCID: https://orcid.org/0000-0002-5107-8209)
- Yuichi Motoyama
- Gaku Yamamichi
- Koji Hatano (ORCID: https://orcid.org/0000-0002-8409-5152)
- Atsunari Kawashima (ORCID: https://orcid.org/0000-0001-9369-4264)
- Shinichiro Fukuhara (ORCID: https://orcid.org/0000-0003-1336-4316)
- Shohei Myoba
- Yu Ishizuya (ORCID: https://orcid.org/0000-0003-0778-1308)
- Yoko Koh (ORCID: https://orcid.org/0000-0001-9976-6994)
- Noriaki Arakawa (ORCID: https://orcid.org/0000-0003-2286-0629)
- Eiichi Morii (ORCID: https://orcid.org/0000-0001-8490-3650)
- Yoshiyuki Yamamoto (ORCID: https://orcid.org/0000-0002-2932-5904)
- Yoko Ino
- Taigo Kato (ORCID: https://orcid.org/0000-0002-8681-1407)
- Norio Nonomura (ORCID: https://orcid.org/0000-0002-6522-6233)
- Motohide Uemura
- Hidetatsu Outani (ORCID: https://orcid.org/0000-0002-5407-5855)
- Hiroji Uemura
- Takeshi Ujike
Institutions
- Fukushima Medical University (JP)
- Yokohama City University Medical Center (JP)
- National Institute of Health Sciences (JP)
- Tosoh (Japan) (JP)
- Yokohama City University (JP)
- The University of Osaka (JP)
Publication Details
- Journal
- Biomarker Research
- Published
- 2024-11-25
- DOI
- https://doi.org/10.1186/s40364-024-00695-6
- Citations
- 6
- Primary Topic
- GDF15 and Related Biomarkers
- Type
- article
- Field-Weighted Citation Impact
- 2.82
Funders
- Japan Society for the Promotion of Science