Intravenous injection of BMSCs modulate tsRNA expression and ameliorate lung remodeling in COPD mice
Our study provides insights into selecting MSC and MSC-EV administration routes for different COPD stages. High-throughput sequencing supports BMSCs' inhibitory effects on lung remodeling and identifies the first tsRNA expression profile in a COPD model, warranting further investigation.
Authors
- Shenghua Sun
- G. Li
- Xianyang Liu
- Ting Jin
- Lihua Xie (ORCID: https://orcid.org/0009-0007-2394-9090)
Institutions
- Central South University (CN)
- Third Xiangya Hospital (CN)
Publication Details
- Journal
- Stem Cell Research & Therapy
- Published
- 2024-11-25
- DOI
- https://doi.org/10.1186/s13287-024-04066-8
- Citations
- 15
- Primary Topic
- RNA modifications and cancer
- Type
- article
- Field-Weighted Citation Impact
- 3.51
Funders
- National Natural Science Foundation of China
- Natural Science Foundation of Hunan Province