Parental epigenetic age acceleration and risk of adverse birth outcomes: the Norwegian mother, father and child cohort study
Maternal, but not paternal, epigenetic age acceleration is associated with shorter pregnancies and an increased risk of spontaneous preterm birth. This may suggest that women's biological age acceleration, including factors such as metabolic and physiologic state, is an additional risk factor for preterm delivery, beyond chronological age.
Authors
- Per Magnus (ORCID: https://orcid.org/0000-0002-6427-4735)
- Cecilia Høst Ramlau‐Hansen (ORCID: https://orcid.org/0000-0003-3296-0121)
- Astanand Jugessur (ORCID: https://orcid.org/0000-0003-1365-8322)
- Lise A Arge (ORCID: https://orcid.org/0000-0002-4710-3221)
- Liv Grimstvedt Kvalvik (ORCID: https://orcid.org/0000-0001-6520-9057)
- Siri E. Håberg (ORCID: https://orcid.org/0000-0002-2199-5225)
- Ellen Øen Carlsen (ORCID: https://orcid.org/0000-0003-1615-5536)
- Maria C. Magnus (ORCID: https://orcid.org/0000-0002-0568-3774)
- Yunsung Lee (ORCID: https://orcid.org/0000-0002-2512-1082)
- Nils‐Halvdan Morken (ORCID: https://orcid.org/0000-0002-8256-0778)
- Mikko Myrskylä
Institutions
- Norwegian Institute of Public Health (NO)
- University of Helsinki (FI)
- Aarhus University (DK)
- Haukeland University Hospital (NO)
- Max Planck Institute for Demographic Research (DE)
- University of Bergen (NO)
Publication Details
- Journal
- BMC Medicine
- Published
- 2024-11-25
- DOI
- https://doi.org/10.1186/s12916-024-03780-7
- Citations
- 1
- Primary Topic
- Birth, Development, and Health
- Type
- article
- Field-Weighted Citation Impact
- 1.11
Funders
- Norwegian Institute of Public Health