Road traffic noise and breast cancer: DNA methylation in four core circadian genes
In summary, our data suggest that DNA hypomethylation in CRY1 and BMAL1 could be part of a causal chain from road traffic noise to breast cancer. This is consistent with the hypothesis that disruption of the circadian rhythm, e.g., from road traffic noise exposure, increases the risk of breast cancer. Since no prior studies have explored this association, it is essential to replicate our results.
Authors
- Mathilde Delaval (ORCID: https://orcid.org/0000-0002-1340-5336)
- Signe Borgquist (ORCID: https://orcid.org/0000-0001-7938-8893)
- Jesse Daniel Thacher (ORCID: https://orcid.org/0000-0003-4908-9715)
- Mette Sørensen (ORCID: https://orcid.org/0000-0002-7302-4789)
- María Albin (ORCID: https://orcid.org/0000-0002-6613-4437)
- Ulrike Maria Dauter
- Karin Bröberg (ORCID: https://orcid.org/0000-0002-5862-468X)
- Kristoffer Mattisson (ORCID: https://orcid.org/0000-0002-3334-9458)
- Anna Oudin (ORCID: https://orcid.org/0000-0002-9876-0627)
- Anastasiia Snigireva (ORCID: https://orcid.org/0000-0003-4501-3860)
Institutions
- Roskilde University (DK)
- Lund University (SE)
- Aarhus University Hospital (DK)
- Karolinska Institutet (SE)
- Helmholtz Zentrum München (DE)
- Skåne University Hospital (SE)
- Danish Cancer Society (DK)
Publication Details
- Journal
- Clinical Epigenetics
- Published
- 2024-11-25
- DOI
- https://doi.org/10.1186/s13148-024-01774-z
- Citations
- 4
- Primary Topic
- Noise Effects and Management
- Type
- article
- Field-Weighted Citation Impact
- 3.49
Funders
- Lunds Universitet
- Vetenskapsrådet
- Forskningsrådet om Hälsa, Arbetsliv och Välfärd