Human Blood Non-Classical/Classical Monocyte Cells Are Heterogeneously Presented in Severe COVID-19 and Correlate with Disease Activity
As supported, regarding cytokine profile in context of SARS-CoV-2 infection, it was identified that circulating NC cells are proinflammatory cells most related to regulatory cells, while CL subset displayed an effective capacity to virus. These findings have implications toward optimizing evaluation in severe COVID-19, and developing strategies that target altered balance of NC/CL cell subsets.
Authors
- Yang Wang (ORCID: https://orcid.org/0000-0002-6527-864X)
- Shen Yu (ORCID: https://orcid.org/0009-0009-5992-288X)
- Cheng Chen (ORCID: https://orcid.org/0000-0002-4636-6433)
- Jing Song (ORCID: https://orcid.org/0000-0001-5314-9405)
- Dong Qiu (ORCID: https://orcid.org/0000-0001-7025-2949)
- Qiu‐Xia Qu (ORCID: https://orcid.org/0000-0002-2836-2092)
- Danhong Zhou (ORCID: https://orcid.org/0000-0003-3933-5185)
Institutions
- Soochow University (CN)
- Suzhou Research Institute (CN)
- First Affiliated Hospital of Soochow University (CN)
Publication Details
- Journal
- Journal of Innate Immunity
- Published
- 2024-11-25
- DOI
- https://doi.org/10.1159/000542652
- Primary Topic
- Diabetes and associated disorders
- Type
- article
- Field-Weighted Citation Impact
- 0.00
Funders
- Natural Science Foundation of Suzhou City