Prospective Randomized Pilot Study Comparing Bivalirudin Versus Heparin in Neonatal and Pediatric Extracorporeal Membrane Oxygenation
In this single-center pilot RCT carried out 2018-2021, we found that the test of anticoagulation therapy of bivalirudin vs. heparin during ECMO was feasible. Larger multicenter studies are required to further assess the safety and efficacy of bivalirudin for pediatric ECMO.
Authors
- Laura Hatton
- Xilong Li (ORCID: https://orcid.org/0000-0002-5742-7043)
- Lakshmi Raman
- Ayesha N Zia (ORCID: https://orcid.org/0000-0003-3283-0415)
- Ali McMichael (ORCID: https://orcid.org/0000-0001-7416-4620)
- Jamie Weller
Institutions
- Children's Medical Center (US)
- The University of Texas Southwestern Medical Center (US)
Publication Details
- Journal
- Pediatric Critical Care Medicine
- Published
- 2024-11-25
- DOI
- https://doi.org/10.1097/pcc.0000000000003642
- Citations
- 10
- Primary Topic
- Mechanical Circulatory Support Devices
- Type
- article
- Field-Weighted Citation Impact
- 1.84
Funders
- American Heart Association
- National Institutes of Health