Effect of anti-sclerostin antibody on orthodontic tooth movement in ovariectomized rats
Romosozumab initially accelerated tooth movements, but later decreased tooth movement. As new alveolar bone is formed, the micro-CT parameters are also improved. Osteoclasts, RANKL, OPG, and sclerostin decreased, while the OPG/RANKL ratio became higher.
Authors
- Jisun Huh
- Namki Hong (ORCID: https://orcid.org/0000-0002-8246-1956)
- Incheol Park (ORCID: https://orcid.org/0000-0001-7033-766X)
- Seoyeon Jung (ORCID: https://orcid.org/0000-0002-0924-9633)
- Hyun-Na Ahn
- Sung-Hwan Choi
Institutions
- Yonsei University (KR)
- Severance Hospital (KR)
- Yonsei University Dental Hospital (KR)
- Yonsei University Health System (KR)
- Yonsei University College of Dentistry
Publication Details
- Journal
- Progress in Orthodontics
- Published
- 2024-11-24
- DOI
- https://doi.org/10.1186/s40510-024-00544-0
- Citations
- 6
- Primary Topic
- Bone Metabolism and Diseases
- Type
- article
- Field-Weighted Citation Impact
- 1.40
Funders
- National Research Foundation
- National Research Foundation of Korea