The Early Youth Engagement (EYE-2) intervention in first-episode psychosis services: pragmatic cluster randomised controlled trial and cost-effectiveness evaluation
We found no evidence that EYE-2 increased time to disengagement, but there was some evidence for its cost-effectiveness. This is the largest study to date reporting positive engagement, health and cost outcomes in a total EIP population sample. Limitations included high loss to follow-up for secondary outcomes and low completion of societal and socio-occupational data. COVID-19 affected fidelity and implementation. Future engagement research should target engagement to those in greatest need, including in-patients and those with socio-occupational goals.
Authors
- Gergely Bartl (ORCID: https://orcid.org/0000-0002-5947-1304)
- Richard de Visser (ORCID: https://orcid.org/0000-0003-1174-1499)
- Rebecca M. Jarvis (ORCID: https://orcid.org/0000-0002-6297-4906)
- Anastacia O’Donnell (ORCID: https://orcid.org/0000-0003-2988-6696)
- Richard Hooper (ORCID: https://orcid.org/0000-0002-1063-0917)
- Stephen Bremner (ORCID: https://orcid.org/0000-0003-0790-7070)
- Emmanuelle Peters (ORCID: https://orcid.org/0000-0003-3327-9223)
- Nahel Yaziji (ORCID: https://orcid.org/0000-0002-2273-7957)
- Louise Johns (ORCID: https://orcid.org/0000-0003-3355-3202)
- Heather Law (ORCID: https://orcid.org/0000-0002-1889-9179)
- Christopher I. Jones (ORCID: https://orcid.org/0000-0001-7065-1157)
- Shanaya Rathod (ORCID: https://orcid.org/0000-0001-5126-3503)
- Jenny Gu (ORCID: https://orcid.org/0000-0003-3660-4204)
- I Abramowiçz (ORCID: https://orcid.org/0000-0001-7500-3597)
- Carl May (ORCID: https://orcid.org/0000-0002-0451-2690)
- Rose Thompson (ORCID: https://orcid.org/0000-0002-2283-6963)
- Peter Phiri (ORCID: https://orcid.org/0000-0001-9950-3254)
- D. Fowler (ORCID: https://orcid.org/0000-0002-2999-2627)
- Belinda Lennox (ORCID: https://orcid.org/0000-0002-4972-8786)
- Kathryn Greenwood (ORCID: https://orcid.org/0000-0001-7899-8980)
- Tanya Mackay (ORCID: https://orcid.org/0000-0002-3208-2077)
- Paul French (ORCID: https://orcid.org/0000-0003-4300-387X)
- Philippa Garety (ORCID: https://orcid.org/0000-0002-5637-1340)
- James Plaistow (ORCID: https://orcid.org/0000-0001-9457-5355)
- Andrew Healey (ORCID: https://orcid.org/0000-0003-2013-3161)
- Sunil Nandha (ORCID: https://orcid.org/0000-0003-4947-5210)
- Rebecca Webb (ORCID: https://orcid.org/0000-0002-8862-6491)
- Jo Hodgekins
- Stuart Clark (ORCID: https://orcid.org/0000-0002-8572-2154)
- M Painter (ORCID: https://orcid.org/0000-0001-6746-4035)
Institutions
- Brighton and Sussex Medical School (GB)
- University of East Anglia (GB)
- Manchester Metropolitan University (GB)
- Greater Manchester Mental Health NHS Foundation Trust (GB)
- University of Sussex (GB)
- Queen Mary University of London (GB)
- King's College London (GB)
- South London and Maudsley NHS Foundation Trust (GB)
- Sussex Partnership NHS Foundation Trust (GB)
- Southern Health NHS Foundation Trust (GB)
- University of Oxford (GB)
- London School of Hygiene & Tropical Medicine (GB)
- Faculty of Public Health (GB)
- McPin Foundation (GB)
- Pennine Care NHS Foundation Trust (GB)
- Cambridgeshire and Peterborough NHS Foundation Trust (GB)
Publication Details
- Journal
- The British Journal of Psychiatry
- Published
- 2024-11-25
- DOI
- https://doi.org/10.1192/bjp.2024.154
- Citations
- 2
- Primary Topic
- Schizophrenia research and treatment
- Type
- article
- Field-Weighted Citation Impact
- 0.77
Funders
- Queen Mary University of London
- London School of Hygiene and Tropical Medicine
- Manchester Metropolitan University
- Sussex Partnership NHS Foundation Trust
- National Institute for Health and Care Research
- University of East Anglia
- King's College London
- University of Oxford
- University of Sussex
- Health Services and Delivery Research Programme