Intraocular complement activation is independent of systemic complement activation and is related to macular vascular remodelling in retinal vein occlusion
The intraocular complement activation in RVO is mediated by the classical and the alternative pathways and is largely independent of systemic complement activation. Intraocular complement activation may be related to retinal oedema and vascular remodeling in RVO patients.
Authors
- Heping Xu (ORCID: https://orcid.org/0000-0003-4000-931X)
- Jinyan Qi
- Tingting Guo (ORCID: https://orcid.org/0009-0007-4482-5564)
- Juan Chen (ORCID: https://orcid.org/0000-0001-5801-9124)
- Jie Wang (ORCID: https://orcid.org/0000-0002-7491-7001)
- Zhongping Chen (ORCID: https://orcid.org/0000-0002-5289-1584)
- Hengwei Liu
- Shengnan Liang (ORCID: https://orcid.org/0009-0008-2632-5096)
- Yufan Zhou (ORCID: https://orcid.org/0000-0003-2607-2718)
- Huanhuan Tan
Institutions
- Queen's University Belfast (GB)
- Central South University (CN)
- Jinan University (CN)
- Hubei University of Science and Technology (CN)
- He Eye Hospital (CN)
Publication Details
- Journal
- BMC Ophthalmology
- Published
- 2024-11-25
- DOI
- https://doi.org/10.1186/s12886-024-03781-3
- Citations
- 5
- Primary Topic
- Retinal Diseases and Treatments
- Type
- article
- Field-Weighted Citation Impact
- 2.69
Funders
- Natural Science Foundation of Hainan Province