Hepatic Events During Immune Checkpoint Inhibitor Treatment Between Liver and Non‐Liver Malignancies in Hepatitis B Endemic Areas

Under ICI treatment, HCC patients had a higher risk of hepatitis flare events than non-HCC patients. Abnormal baseline ALT levels are a risk factor for hepatic adverse events. NUC prophylaxis can minimise the risk of HBVr.

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Publication Details

Journal
Alimentary Pharmacology & Therapeutics
Published
2024-11-24
DOI
https://doi.org/10.1111/apt.18403
Citations
12
Primary Topic
Hepatitis B Virus Studies
Type
article
Field-Weighted Citation Impact
4.64

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article

Hepatic Events During Immune Checkpoint Inhibitor Treatment Between Liver and Non‐Liver Malignancies in Hepatitis B Endemic Areas

Muh‐Hwa Yang, Pei‐Chang Lee, Yee Chao, Ming‐Chih Hou et al.
12 citations
Alimentary Pharmacology & Therapeutics
Hepatitis B Virus Studies
4.64
article

Hepatic Events During Immune Checkpoint Inhibitor Treatment Between Liver and Non‐Liver Malignancies in Hepatitis B Endemic Areas

Muh‐Hwa Yang, Pei‐Chang Lee, Yee Chao, Ming‐Chih Hou, Yi‐Ping Hung, I‐Cheng Lee, Yi‐Hsiang Huang, Chao‐Hua Chiu, Keng‐Hsin Lan, Ming‐Huang Chen, Yen‐Hwa Chang
article en
12 citations

Abstract

Under ICI treatment, HCC patients had a higher risk of hepatitis flare events than non-HCC patients. Abnormal baseline ALT levels are a risk factor for hepatic adverse events. NUC prophylaxis can minimise the risk of HBVr.

Alimentary Pharmacology & TherapeuticsVol. 61(3)
National Yang Ming Chiao Tung University (TW), Taipei Veterans General Hospital (TW)
Taiwan Clinical Oncology Research Foundation, Taipei Veterans General Hospital, National Science and Technology Council
Good health and well-being
Openalex Percentile: Top 4%
Hepatitis B Virus Studies
4.64
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