Vestibular afferent neurons develop normally in the absence of quantal/glutamatergic input
Thus, unlike in the auditory nerve, glutamatergic signaling is unnecessary for producing biophysical diversity in vestibular ganglion neurons. And yet, because the input signals from vestibular hair cells are complex and not solely reliant on quantal release of glutamate, whether diversity of vestibular ganglion neurons is simply hardwired or regulated by a more complex set of input signals remains to be determined.
Authors
- Radha Kalluri (ORCID: https://orcid.org/0000-0002-0360-8965)
- Daniel R. Bronson (ORCID: https://orcid.org/0000-0002-3899-9521)
- Katherine Regalado Núñez
- Ryan Chang (ORCID: https://orcid.org/0000-0002-9710-8047)
Institutions
- University of Southern California (US)
Publication Details
- Journal
- Frontiers in Neurology
- Published
- 2024-11-25
- DOI
- https://doi.org/10.3389/fneur.2024.1441964
- Citations
- 4
- Primary Topic
- Vestibular and auditory disorders
- Type
- article
- Field-Weighted Citation Impact
- 0.99
Funders
- National Institutes of Health
- National Institute on Deafness and Other Communication Disorders