Impact of Vitiligo on Fasting Blood Sugar and Thyroid Hormone Profile on Libyan Patients

Vitiligo is a common acquired skin disease characterized by the development of circumscribed white patches of skin. It affects 1-2% of the general population. Autoimmunity plays a significant role in the pathophysiology of vitiligo. This study was intended to assess the prevalence and association of fasting blood sugar and thyroid function abnormalities among Vitiligo patients and healthy controls. A case-control study was carried out among thirty patients with a confirmed diagnosis of vitiligo (53.3% female and 46.7% male) who attended Tripoli Central Hospital (TCH) and Tajoura Hospital for follow-up, and a matched number of control subjects were recruited randomly. All blood samples were collected to assay for the FBS test, triiodothyronine (T3), thyroxin (T4), and thyroid-stimulating hormone (TSH). According to the recent data, the mean age of patients who were involved in this study was 34.4±16.51 years, while the mean age of onset was 20.13 ±14.19. Additionally, the data revealed that there were significant differences in FBS between vitiligo patients and healthy control groups (p-value = <0.001). Moreover, there were statistically significant differences between vitiligo patients and non-vitiligo subjects in T4 (p-value = 0.042). Furthermore, there was no significant correlation between the vitiligo phenotypes and thyroid hormone levels. P-value = 0.911 Chi-Square = 0.186. According to the results of the present study, it appears that vitiligo affects both sexes, especially women. It has also been noted that generalized vitiligo was more common, and there was no correlation between patterns of vitiligo and thyroid state.