Semen Cuscutae flavonoids activated the cAMP-PKA-CREB-BDNF pathway and exerted an antidepressant effect in mice
SCFs could ameliorate hippocampal metabolic disturbances and depressive behaviors and cause the activation of the cAMP-PKA-CREB-BDNF signaling pathway in the hippocampus of CUMS mice.
Authors
- Guangbin Luo (ORCID: https://orcid.org/0000-0002-5851-3760)
- Jin Lin (ORCID: https://orcid.org/0000-0003-1540-9565)
- Xiaowei Fu
- Qianfeng Shao
- Yue Li (ORCID: https://orcid.org/0000-0002-7727-905X)
- Shaohui Du (ORCID: https://orcid.org/0000-0002-0247-6112)
- Che Chen (ORCID: https://orcid.org/0000-0001-5156-2431)
- Sheng Zhou (ORCID: https://orcid.org/0000-0001-8896-1006)
- Tong Liu (ORCID: https://orcid.org/0000-0002-1157-8890)
Institutions
- Guangzhou University of Chinese Medicine (CN)
- Beijing University of Chinese Medicine (CN)
- Ningxia Medical University (CN)
- University School (US)
- Shenzhen Pingle Orthopedic Hospital (CN)
- Case Western Reserve University (US)
Publication Details
- Journal
- Frontiers in Pharmacology
- Published
- 2024-11-25
- DOI
- https://doi.org/10.3389/fphar.2024.1491900
- Citations
- 6
- Primary Topic
- Sirtuins and Resveratrol in Medicine
- Type
- article
- Field-Weighted Citation Impact
- 2.07
Funders
- National Natural Science Foundation of China