The causal relationship between type 2 diabetes mellitus and isolated REM sleep behavior disorder: results from multivariable and network Mendelian randomization analysis

T2DM may promote the onset of iRBD by influencing immune-inflammatory responses. Our findings provide valuable insights and directions for understanding the pathogenesis of iRBD, identifying high-risk groups, and discovering new therapeutic targets.

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Publication Details

Journal
Frontiers in Endocrinology
Published
2024-11-25
DOI
https://doi.org/10.3389/fendo.2024.1408053
Primary Topic
Genetic Associations and Epidemiology
Type
article
Field-Weighted Citation Impact
0.00
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article

The causal relationship between type 2 diabetes mellitus and isolated REM sleep behavior disorder: results from multivariable and network Mendelian randomization analysis

Fu-Jia Li, Ru-Yu Zhang, Jie Zhao, Jin-Yu Li et al.
1 links
Frontiers in Endocrinology
Genetic Associations and Epidemiology
article

The causal relationship between type 2 diabetes mellitus and isolated REM sleep behavior disorder: results from multivariable and network Mendelian randomization analysis

Fu-Jia Li, Ru-Yu Zhang, Jie Zhao, Jin-Yu Li, Yu-Ning Liu, Zi-Xuan Zhang
article en

Abstract

T2DM may promote the onset of iRBD by influencing immune-inflammatory responses. Our findings provide valuable insights and directions for understanding the pathogenesis of iRBD, identifying high-risk groups, and discovering new therapeutic targets.

Frontiers in EndocrinologyVol. 15
Sun Yat-sen University (CN), Xuzhou Medical College (CN), Zigong First People's Hospital (CN), Eighth Affiliated Hospital of Sun Yat-sen University
Good health and well-being
Openalex Percentile: Top 76%
Genetic Associations and Epidemiology
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