Skin Metastasis From Solid Tumors: Is Targeted Therapy Making an Impact?

Cutaneous metastasis from solid tumors is a rare manifestation that presents in the clinic. It is usually indicative of poor prognosis, with a poor response to conventional chemotherapy. The introduction of targeted therapy has changed the treatment paradigm in oncology, improving the quality of life and survival of all cancer patients. Here, we present two cases of solid tumors with skin metastases that had a good response to targeted systemic therapy. This case report also discusses the various modes of presentation and the therapeutic options for metastatic cutaneous lesions from solid tumors.