Macrophage-derived cathepsin L promotes epithelial-mesenchymal transition and M2 polarization in gastric cancer

In consideration of our findings, tumor-associated macrophage-derived CTSL is an important factor that promotes the metastasis and invasion of gastric cancer cells, and the targeting of CTSL may potentially improve the prognosis of patients with gastric cancer with peritoneal metastasis.

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Publication Details

Journal
World Journal of Gastroenterology
Published
2024-11-25
DOI
https://doi.org/10.3748/wjg.v30.i47.5032
Citations
5
Primary Topic
Inflammatory Biomarkers in Disease Prognosis
Type
article
Field-Weighted Citation Impact
1.41
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article

Macrophage-derived cathepsin L promotes epithelial-mesenchymal transition and M2 polarization in gastric cancer

Man-Sheng Zhu, Ri-Xiang Qiu, Haiyi Yu, Weiwei Ding et al.
5 citations
World Journal of Gastroenterology
Inflammatory Biomarkers in Disease Prognosis
1.41
article

Macrophage-derived cathepsin L promotes epithelial-mesenchymal transition and M2 polarization in gastric cancer

Man-Sheng Zhu, Ri-Xiang Qiu, Haiyi Yu, Weiwei Ding, X. Li, Zhonghua Wu, Tao Chen, Yang Jia, Yu Jiang, Zhen Zhai, Li‐Na Xiao, Chuanfa Fang
article en
5 citations

Abstract

In consideration of our findings, tumor-associated macrophage-derived CTSL is an important factor that promotes the metastasis and invasion of gastric cancer cells, and the targeting of CTSL may potentially improve the prognosis of patients with gastric cancer with peritoneal metastasis.

World Journal of GastroenterologyVol. 30(47)
Ganzhou People's Hospital (CN), Hubei University of Arts and Science (CN), Central Hospital of Wuhan (CN), Southern Medical University (CN)
Openalex Percentile: Top 15%
Inflammatory Biomarkers in Disease Prognosis
1.41
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