Associations of demyelination in the right middle temporal gyrus and right praecuneus with visuospatial cognitive dysfunction in Alzheimer's disease
Our results demonstrated a strong association between reduced myelin integrity in the right middle temporal gyrus and right praecuneus and visuospatial cognitive dysfunction in patients with AD. These findings are believed to shed light on the neural basis of visuospatial processing in patients with AD, underlining the necessity for developing objective biomarkers for assessing patients' visuospatial cognitive function.
Authors
- Toshiteru Miyasaka (ORCID: https://orcid.org/0000-0002-0551-0929)
- Hiroaki Yoshikawa (ORCID: https://orcid.org/0000-0002-6350-5183)
- Tomoko Ochi
- Toshihiro Tanaka (ORCID: https://orcid.org/0000-0001-6201-9784)
- Kuniaki Kiuchi (ORCID: https://orcid.org/0000-0003-3305-5270)
- Kiwamu Matsuoka (ORCID: https://orcid.org/0000-0003-3263-0958)
- Yuka Fujimoto (ORCID: https://orcid.org/0000-0002-6865-8998)
- Ryohei Matsumoto (ORCID: https://orcid.org/0009-0000-5001-4150)
- Takashi Okada (ORCID: https://orcid.org/0000-0001-5580-9913)
- Manabu Makinodan (ORCID: https://orcid.org/0000-0003-4339-9413)
- Masato Takahashi (ORCID: https://orcid.org/0000-0003-3265-0166)
- Akihiro Minami
- Kazuya Ueda
- Hideyuki Ohnishi
Institutions
- Kyoto Prefectural University (JP)
- Kyoto Prefectural University of Medicine (JP)
- Osaka City General Hospital (JP)
- Nara Medical University Hospital (JP)
- Higashi Osaka City General Hospital (JP)
- Nara Medical University (JP)
Publication Details
- Journal
- Psychogeriatrics
- Published
- 2024-11-24
- DOI
- https://doi.org/10.1111/psyg.13223
- Citations
- 4
- Primary Topic
- Dementia and Cognitive Impairment Research
- Type
- article
- Field-Weighted Citation Impact
- 1.54