Tropism of adeno-associated virus serotypes in mouse lungs via intratracheal instillation
Our findings provide comprehensive information about the tropism of AAVs in pulmonary epithelium in mice, which might be helpful in developing efficient AAV-mediated gene therapy strategies for pulmonary disease treatment.
Authors
- Wenguang Yin (ORCID: https://orcid.org/0000-0003-1722-8637)
- Lang He (ORCID: https://orcid.org/0000-0002-2235-7495)
- Ye Bu
- Yao Dong (ORCID: https://orcid.org/0000-0001-8883-5384)
- Aichun Zhao (ORCID: https://orcid.org/0000-0001-6140-0102)
- Haoyu Wu (ORCID: https://orcid.org/0000-0002-8995-3486)
- Wei-Ping Yang
- Huapeng Li (ORCID: https://orcid.org/0000-0002-4394-2220)
- Yujian Zhong (ORCID: https://orcid.org/0000-0002-7043-642X)
Institutions
- Guilin Medical University (CN)
- Guangzhou Experimental Station (CN)
- First Affiliated Hospital of Guangzhou Medical University (CN)
- State Key Laboratory of Respiratory Disease (CN)
- Guangzhou Medical University (CN)
Publication Details
- Journal
- Virology Journal
- Published
- 2024-11-25
- DOI
- https://doi.org/10.1186/s12985-024-02575-9
- Citations
- 6
- Primary Topic
- Virus-based gene therapy research
- Type
- article
- Field-Weighted Citation Impact
- 3.30
Funders
- National Natural Science Foundation of China
- Fudan University
- Natural Science Foundation of Guangxi Province
- State Key Laboratory of Genetic Engineering