Porin expression in clinical isolates of Klebsiella pneumoniae: a comparison of SDS-PAGE and MALDI-TOF/MS and limitations of whole genome sequencing analysis
MALDI-TOF/MS was reliable for porin detection, but because of the complex regulation of porin genes, WGS cannot always anticipate protein expression, as observed with SDS-PAGE and MALDI-TOF/MS.
Authors
- Julia Guzmán-Puche (ORCID: https://orcid.org/0000-0003-2199-7949)
- Montserrat Muñoz-Rosa
- Eduardo Chicano‐Gálvez (ORCID: https://orcid.org/0000-0002-9481-9628)
- Cristina Elías-López (ORCID: https://orcid.org/0000-0002-3509-8795)
- Elena Pérez‐Nadales (ORCID: https://orcid.org/0000-0002-6796-1813)
- Luis Martínez-Martínez (ORCID: https://orcid.org/0000-0002-6091-4045)
Institutions
- Instituto de Salud Carlos III (ES)
- Instituto Maimónides de Investigación Biomédica de Córdoba (ES)
- Hospital Universitario Reina Sofía (ES)
- University of Córdoba (ES)
Publication Details
- Journal
- Annals of Clinical Microbiology and Antimicrobials
- Published
- 2024-11-24
- DOI
- https://doi.org/10.1186/s12941-024-00761-9
- Citations
- 6
- Primary Topic
- Antibiotic Resistance in Bacteria
- Type
- article
- Field-Weighted Citation Impact
- 1.02
Funders
- Ministerio de Ciencia e Innovación
- Instituto de Salud Carlos III