Exploring new mechanisms in cancer molecular pathways and pathogenic cell transformation: PIP4K2A as a prognostic marker and therapeutic target in cutaneous malignant melanoma
The PIP4K2A gene could be a crucial prognostic marker for cutaneous malignant melanoma, as it significantly affects T cell activity within the tumor microenvironment. This study offers essential insights into melanoma pathogenesis and assists in pinpointing new early diagnostic markers and therapeutic targets. Utilizing advanced genomic tools and computational techniques, the research enhances our understanding of T cell dynamics in melanoma, facilitating the development of personalized medicine and more effective immunotherapy strategies.
Authors
- Tong Shen (ORCID: https://orcid.org/0000-0001-8558-2086)
- Yibo He (ORCID: https://orcid.org/0000-0002-8043-4727)
- Hongyang Du (ORCID: https://orcid.org/0000-0002-8220-6525)
- Lingling Fang (ORCID: https://orcid.org/0000-0003-2938-9155)
- M. Si.
- Ding-ming Song
- Wen-fei Luo
Institutions
- Zhejiang Chinese Medical University (CN)
- Jinzhou Medical University (CN)
Publication Details
- Journal
- Discover Oncology
- Published
- 2024-11-23
- DOI
- https://doi.org/10.1007/s12672-024-01555-3
- Citations
- 4
- Primary Topic
- Melanoma and MAPK Pathways
- Type
- article
- Field-Weighted Citation Impact
- 0.94