Sex hormones, blood metabolites and proteins mediating the causal associations between gut microbiota and prostatic diseases: evidences from Mendelian randomization study
Our study represents the first comprehensive exploration of the causal effects of the gut microbiota on prostatic diseases and reveals the mediating effects of sex hormones and blood metabolites on the "gut-prostate axis."
Authors
- Jialin Meng (ORCID: https://orcid.org/0000-0002-4622-833X)
- Kun Wang (ORCID: https://orcid.org/0000-0002-0631-1323)
- Tianrui Liu (ORCID: https://orcid.org/0000-0001-7091-9432)
- Yunyun Mei (ORCID: https://orcid.org/0000-0002-0924-7451)
- Hao Li (ORCID: https://orcid.org/0000-0002-1767-6475)
- Yang Zhang (ORCID: https://orcid.org/0000-0002-0789-4938)
- Xiangyu Zhang (ORCID: https://orcid.org/0000-0001-8415-0003)
- Yiding Chen
- Zhige Wang
- Feixiang Yang
Institutions
- Xiamen University (CN)
- Anhui Medical University (CN)
- Fudan University Shanghai Cancer Center (CN)
- First Affiliated Hospital of Anhui Medical University (CN)
- Second Affiliated Hospital of Anhui Medical University (CN)
Publication Details
- Journal
- Prostate International
- Published
- 2024-11-23
- DOI
- https://doi.org/10.1016/j.prnil.2024.11.004
- Citations
- 2
- Primary Topic
- Genetic Associations and Epidemiology
- Type
- article
- Field-Weighted Citation Impact
- 1.10
Funders
- National Natural Science Foundation of China
- Anhui Medical University
- Natural Science Foundation of Anhui Province