Cabotegravir Maintains Protective Efficacy in the Setting of Bacterial Sexually Transmitted Infections: A Secondary Analysis of HPTN 083
In a large preexposure prophylaxis trial with high STI incidence, CAB-LA maintained robust protective efficacy relative to TDF/FTC in the setting of bacterial STIs.
Authors
- Jorge A. Gallardo-Cartagena (ORCID: https://orcid.org/0000-0001-5142-1954)
- Anne Rompalo
- Jessica Amber Jennings (ORCID: https://orcid.org/0000-0002-2760-6948)
- Carl J. Fichtenbaum (ORCID: https://orcid.org/0000-0002-6778-7253)
- Juan Carlos Hinojosa Boyer
- Meredith E. Clement (ORCID: https://orcid.org/0000-0002-0283-6368)
- Edgar T. Overton (ORCID: https://orcid.org/0000-0002-4013-536X)
- Kailazarid Gomez Feliciano (ORCID: https://orcid.org/0000-0001-5849-8372)
- Christopher B. Hurt (ORCID: https://orcid.org/0000-0003-3290-8200)
- Richard Novák (ORCID: https://orcid.org/0000-0003-0485-4284)
- Breno Santos (ORCID: https://orcid.org/0000-0002-2888-2573)
- Jessica Justman
- Beatriz Gilda Jegerhorn Grinsztejn (ORCID: https://orcid.org/0000-0003-3692-5155)
- Kenneth Hugh Mayer (ORCID: https://orcid.org/0000-0001-7460-733X)
- Daniel Reirden (ORCID: https://orcid.org/0000-0002-4391-2718)
- Nuntisa Chotirosniramit (ORCID: https://orcid.org/0000-0001-9066-4772)
- Roberto C. Arduino (ORCID: https://orcid.org/0000-0002-7381-844X)
- Shobha Swaminathan (ORCID: https://orcid.org/0000-0001-8609-3073)
- Keren Middelkoop (ORCID: https://orcid.org/0000-0001-9922-4263)
- Rachel M. Presti (ORCID: https://orcid.org/0000-0002-5469-0727)
- Raphael J. Landovitz (ORCID: https://orcid.org/0000-0002-1442-714X)
- Trần Việt Hà (ORCID: https://orcid.org/0000-0002-8549-4761)
- Marybeth McCauley
- Sharon Mannheimer (ORCID: https://orcid.org/0000-0002-6813-1539)
- James F. Rooney (ORCID: https://orcid.org/0000-0003-3261-0711)
- Aditya H. Gaur (ORCID: https://orcid.org/0000-0002-6639-5231)
- Nittaya Phanuphak (ORCID: https://orcid.org/0000-0002-0036-3165)
- Albert Liu (ORCID: https://orcid.org/0000-0003-0320-823X)
- Mayara Secco Torres Silva (ORCID: https://orcid.org/0000-0002-0195-0337)
- Julie Franks (ORCID: https://orcid.org/0000-0001-6329-2301)
- Omar Sued (ORCID: https://orcid.org/0000-0001-5818-770X)
- Roy M. Gulick (ORCID: https://orcid.org/0000-0002-1431-8912)
- Eileen F. Dunne (ORCID: https://orcid.org/0000-0002-9634-1808)
- Jesse L. Clark (ORCID: https://orcid.org/0000-0001-5862-6530)
- Ian Frank (ORCID: https://orcid.org/0000-0002-7824-0106)
- Pedro Gonzáles (ORCID: https://orcid.org/0000-0003-0154-0087)
- Manya Magnus (ORCID: https://orcid.org/0000-0002-6359-987X)
- Carlos del Rı́o (ORCID: https://orcid.org/0000-0002-0153-3517)
- Temitope Oyedele
- Marcelo Losso (ORCID: https://orcid.org/0000-0002-4273-4833)
- Ryan Kofron (ORCID: https://orcid.org/0000-0002-9748-6531)
- Colleen F. Kelley (ORCID: https://orcid.org/0000-0001-5611-0119)
- Christopher Hall (ORCID: https://orcid.org/0000-0001-6156-4975)
- Brett Hanscom (ORCID: https://orcid.org/0000-0003-0618-2979)
- Alex R. Rinehart
- Lydia Soto-Torres
- Suwat Chariyalertsak (ORCID: https://orcid.org/0000-0002-3711-7144)
- Cornelius van Dam
- Sue Ellen Abdalian
- José A. Bazan (ORCID: https://orcid.org/0000-0002-8405-7156)
- Daniel Haines
- Robinson Cabello
Institutions
- Family Health International 360 (US)
- Beth Israel Deaconess Medical Center (US)
- Harvard University (US)
- University of California, Los Angeles (US)
- Columbia University Irving Medical Center (US)
- National Institute of Infectious Diseases (JP)
- Fred Hutch Cancer Center (US)
- ViiV Healthcare (United Kingdom) (GB)
- National Institute of Allergy and Infectious Diseases (US)
- Statistics Collaborative (US)
- Gilead Sciences (United States) (US)
- Gilead Sciences (Australia) (AU)
- Fenway Health (US)
- Chiang Mai University (TH)
- Fundação Oswaldo Cruz (BR)
- The Ohio State University (US)
- Louisiana State University Health Sciences Center New Orleans (US)
- Columbia University (US)
Publication Details
- Journal
- Clinical Infectious Diseases
- Published
- 2024-11-19
- DOI
- https://doi.org/10.1093/cid/ciae572
- Primary Topic
- HIV/AIDS Research and Interventions
- Type
- article
- Field-Weighted Citation Impact
- 0.00