A reference quality, fully annotated diploid genome from a Saudi individual
We have used multiple sequencing approaches to sequence the genome of a volunteer from Saudi Arabia. We use the resulting data to generate a de novo assembly of the genome, and use different computational approaches to refine the assembly. As a consequence, we provide a contiguous assembly of the complete genome of an individual from Saudi Arabia for all chromosomes except chromosome Y, and label this assembly KSA001. We transferred genome annotations from reference genomes to fully annotate KSA001, and we make all primary sequencing data, the assembly, and the genome annotations freely available in public databases using the FAIR data principles. KSA001 is the first telomere-to-telomere-assembled genome from a Saudi individual that is freely available for any purpose.
Authors
- Salim Bougouffa (ORCID: https://orcid.org/0000-0001-9218-6452)
- Ming Sin Cheung (ORCID: https://orcid.org/0000-0003-3423-4609)
- Ana M. Reyes-Ramos (ORCID: https://orcid.org/0000-0002-7916-0466)
- Azza Althagafi (ORCID: https://orcid.org/0000-0001-6084-8706)
- Hatoon Al Ali (ORCID: https://orcid.org/0000-0001-5303-2338)
- Alexander Putra (ORCID: https://orcid.org/0000-0002-4864-9744)
- Dana Alhattab (ORCID: https://orcid.org/0000-0002-0509-6182)
- Changsook Park (ORCID: https://orcid.org/0000-0003-1515-4574)
- Ebtehal Alsolme (ORCID: https://orcid.org/0000-0001-6638-4164)
- Angel Angelov (ORCID: https://orcid.org/0000-0002-9228-0817)
- Hind Aldakhil (ORCID: https://orcid.org/0000-0001-9491-103X)
- Robert Hoehndorf (ORCID: https://orcid.org/0000-0001-8149-5890)
- Charlotte A. E. Hauser (ORCID: https://orcid.org/0000-0001-8251-7246)
- Marwa Abdelhakim (ORCID: https://orcid.org/0000-0001-6816-2119)
- Malak Abedalthagafi (ORCID: https://orcid.org/0000-0003-1786-3366)
- Rund Tawfiq (ORCID: https://orcid.org/0000-0002-7052-573X)
- Maxat Kulmanov (ORCID: https://orcid.org/0000-0003-1710-1820)
- Patrick Driguez (ORCID: https://orcid.org/0000-0001-8104-677X)
- Yang Liu (ORCID: https://orcid.org/0000-0001-5767-360X)
- Mohammed Alarawi (ORCID: https://orcid.org/0000-0001-8986-8209)
Institutions
- Emory Healthcare (US)
- Emory University (US)
- Taif University (SA)
- King Fahd Medical City (SA)
- Graz University of Technology (AT)
- King Salman Center for Disability Research (SA)
- Max Planck Institute for Biology of Ageing (DE)
- King Abdullah University of Science and Technology (SA)
Publication Details
- Journal
- Scientific Data
- Published
- 2024-11-23
- DOI
- https://doi.org/10.1038/s41597-024-04121-2
- Citations
- 3
- Primary Topic
- Genomics and Phylogenetic Studies
- Type
- article
- Field-Weighted Citation Impact
- 0.70
Funders
- King Abdullah University of Science and Technology