High-grade serous carcinoma occurring after risk-reducing salpingo-oophorectomy in <i>BRCA1/2</i> germline pathogenic variant carriers
In BRCA1/2 GPV carriers, long-term incidence of HGSC after RRSO without pathological findings was low. Strict adherence to guidelines regarding timely RRSO followed by complete specimen embedding can further reduce the risk of HGSC in the years after RRSO.
Authors
- E. Gómez (ORCID: https://orcid.org/0000-0003-4999-8847)
- Katja N. Gaarenstroom (ORCID: https://orcid.org/0000-0002-4702-1680)
- Brigitte F M Slangen (ORCID: https://orcid.org/0000-0003-2811-3851)
- Harry Hollema
- Luc R.C.W. van Lonkhuijzen (ORCID: https://orcid.org/0000-0001-6905-2704)
- Iris A.S. Stroot (ORCID: https://orcid.org/0000-0002-5506-8841)
- Joanne A. de Hullu (ORCID: https://orcid.org/0000-0001-5578-092X)
- Marc van Beurden (ORCID: https://orcid.org/0000-0003-2809-3475)
- Ronald P. Zweemer (ORCID: https://orcid.org/0000-0003-1829-7773)
- Helena C. van Doorn (ORCID: https://orcid.org/0000-0003-1062-4485)
- Marise M. Wagner (ORCID: https://orcid.org/0000-0001-9575-0792)
- Muriel A. Adank (ORCID: https://orcid.org/0000-0002-2417-203X)
- Marijke R. Wevers (ORCID: https://orcid.org/0000-0001-8008-6008)
- Fenne L. Komdeur (ORCID: https://orcid.org/0000-0001-6520-8169)
- Maartje J. Hooning
- Refika Yigit
- Joost Bart
- Christi J van Asperen
- Margreet G. E. M. Ausems
Institutions
- Gynecologic Oncology Group (US)
- University Medical Center Groningen (NL)
- Radboud University Nijmegen (NL)
- University of Groningen (NL)
- Leiden University Medical Center (NL)
- Maastricht University Medical Centre (NL)
- Radboud University Medical Center (NL)
- The Netherlands Cancer Institute (NL)
- University Medical Center Utrecht (NL)
- Maastricht University (NL)
- Netherlands Cancer Institute-Antoni van Leeuwenhoek Hospital (NL)
- Cancer Genomics Centre (NL)
- Cancer Genetics (United States) (US)
- Erasmus MC Cancer Institute (NL)
- Amsterdam University Medical Centers (NL)
- University of Amsterdam (NL)
Publication Details
- Journal
- JNCI Journal of the National Cancer Institute
- Published
- 2024-11-23
- DOI
- https://doi.org/10.1093/jnci/djae300
- Citations
- 4
- Primary Topic
- BRCA gene mutations in cancer
- Type
- article
- Field-Weighted Citation Impact
- 2.20
Funders
- Amsterdam University Medical Centers
- Universiteit Leiden
- Rijksuniversiteit Groningen
- Radboud Universiteit
- Universiteit Maastricht
- Erasmus Medisch Centrum
- Nederlandse Organisatie voor Wetenschappelijk Onderzoek
- Maastricht Universitair Medisch Centrum
- Leids Universitair Medisch Centrum
- Radboud Universitair Medisch Centrum