A cross-tissue transcriptome-wide association study identifies WDPCP as a potential susceptibility gene for coronary atherosclerosis
WDPCP is a potential novel susceptibility gene for CAS, influencing endothelial function, lipid metabolism, and coronary artery development. This study extends GWAS findings, highlighting WDPCP's potential as a therapeutic target and its consistent expression across different tissues. Further validation studies are warranted.
Authors
- Xiaofang Yang (ORCID: https://orcid.org/0000-0002-9798-2658)
- Ning Jackie Zhang (ORCID: https://orcid.org/0009-0003-9444-1535)
- Xinyue Hu
- Guanglei Chen (ORCID: https://orcid.org/0000-0002-8107-628X)
- Jin Cui (ORCID: https://orcid.org/0000-0003-3186-7654)
Institutions
- Guiyang College of Traditional Chinese Medicine (CN)
- Guizhou University (CN)
- Affiliated Hospital of Guizhou Medical University (CN)
- First Teaching Hospital of Tianjin University of Traditional Chinese Medicine (CN)
Publication Details
- Journal
- Atherosclerosis Plus
- Published
- 2024-11-23
- DOI
- https://doi.org/10.1016/j.athplu.2024.11.002
- Citations
- 1
- Primary Topic
- Genetic Associations and Epidemiology
- Type
- article
- Field-Weighted Citation Impact
- 0.55
Funders
- National Natural Science Foundation of China