Electrochemical Radical Allylation Reaction of Arylphosphine Oxides
Abstract Functionalized organophosphorus compounds are key structural motifs in many natural products and pharmaceutical chemicals. Herein, we describe the electrochemical radical allylation reaction for the direct and efficient construction of C(sp 3 )─P bonds. A wide range of arylphosphine oxides and allylsilanes were well tolerated, providing valuable organophosphorus compounds with generally good yields. Mechanistic studies indicate that a phosphoryl radical is generated through a single‐electron transfer oxidation process and plays a pivotal role in the reaction pathway.
Authors
- Jianming Huang (ORCID: https://orcid.org/0000-0002-4767-3021)
- Jin Song (ORCID: https://orcid.org/0000-0002-7432-9461)
- Chang Guo (ORCID: https://orcid.org/0000-0003-4022-9582)
- Qiannan Wang (ORCID: https://orcid.org/0000-0002-7972-0718)
- Xinyu Wang (ORCID: https://orcid.org/0000-0001-7549-2845)
Institutions
- University of Science and Technology of China (CN)
- Anhui University (CN)
- Hefei Institutes of Physical Science (CN)
- Hefei National Center for Physical Sciences at Nanoscale (CN)
Publication Details
- Journal
- ChemCatChem
- Published
- 2024-11-23
- DOI
- https://doi.org/10.1002/cctc.202401650
- Citations
- 1
- Primary Topic
- Radical Photochemical Reactions
- Type
- article
- Field-Weighted Citation Impact
- 0.25
Funders
- National Natural Science Foundation of China
- Natural Science Foundation of Anhui Province