High Colchicine Doses Are Really Silver Bullets Against COVID-19

Abstract The numerous attempts to prove a therapeutic effect of low-dose colchicine for the treatment of Coronavirus disease-2019 (COVID-19) have been discouraging. Increase of doses, however, leads to accumulation in leukocytes and inhibition of the cytokine storm thus preventing COVID-19 complications and hospitalizations. Hospital mortality drops up to 7-fold, while outpatients practically do not reach hospitalization.

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Publication Details

Journal
Acta Medica Bulgarica
Published
2024-11-23
DOI
https://doi.org/10.2478/amb-2024-0085
Citations
2
Primary Topic
COVID-19 Clinical Research Studies
Type
article
Field-Weighted Citation Impact
0.78

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article

High Colchicine Doses Are Really Silver Bullets Against COVID-19

Vanio Mitev
2 citations
Acta Medica Bulgarica
COVID-19 Clinical Research Studies
0.78
article

High Colchicine Doses Are Really Silver Bullets Against COVID-19

Vanio Mitev
article en
2 citations

Abstract

Abstract The numerous attempts to prove a therapeutic effect of low-dose colchicine for the treatment of Coronavirus disease-2019 (COVID-19) have been discouraging. Increase of doses, however, leads to accumulation in leukocytes and inhibition of the cytokine storm thus preventing COVID-19 complications and hospitalizations. Hospital mortality drops up to 7-fold, while outpatients practically do not reach hospitalization.

Acta Medica BulgaricaVol. 51(4)
Medical University of Sofia (BG)
European Commission
Good health and well-being
Openalex Percentile: Top 26%
COVID-19 Clinical Research Studies
0.78
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