Advances in Pelvic Inflammatory Disease (PID): Epidemiology, Pathogenesis and Management

Pelvic Inflammatory Disease (PID) is a complex clinical syndrome that affects the female upper genital tract, including endometritis, salpingitis, oophoritis, and tubo-ovarian abscesses. Its etiology is predominantly associated with ascending infections, primarily by Neisseria gonorrhoeae and Chlamydia trachomatis, although in our population, the microbiota has been observed to play a significant role. PID can lead to serious complications such as adhesive syndrome, which can be a determinant of infertility, chronic pelvic pain, and ectopic pregnancy. This article reviews the global and Mexican epidemiology, pathogenic mechanisms, diagnostic criteria, therapeutic approaches, and current preventive strategies, highlighting the importance of early diagnosis and appropriate treatment to minimize long-term sequelae.