Frontotemporal structure preservation underlies the protective effect of lifetime intellectual cognitive reserve on cognition in the elderly
The new comprehensive cognitive reserve index could promote the temporal macro-structural preservation and thus contribute to maintain better cognitive function. These findings highlight the importance of intellectual CR accumulation over the life course in successful cognitive aging and MCI prevention, thereby contributing to improve the quality of life in the elderly.
Authors
- Mingxi Dang (ORCID: https://orcid.org/0000-0002-3254-8535)
- Shaokun Zhao (ORCID: https://orcid.org/0000-0002-0714-6024)
- Feng Sang (ORCID: https://orcid.org/0000-0002-6427-8541)
- Zhanjun Zhang (ORCID: https://orcid.org/0000-0002-6714-3263)
- Xin Li (ORCID: https://orcid.org/0009-0002-8445-5354)
- Dandan Wang (ORCID: https://orcid.org/0000-0002-6327-8339)
Institutions
- Beijing Normal University (CN)
Publication Details
- Journal
- Alzheimer s Research & Therapy
- Published
- 2024-11-23
- DOI
- https://doi.org/10.1186/s13195-024-01613-6
- Citations
- 3
- Primary Topic
- Dementia and Cognitive Impairment Research
- Type
- article
- Field-Weighted Citation Impact
- 1.16
Funders
- National Natural Science Foundation of China
- State Key Laboratory of Cognitive Neuroscience and Learning
- National Key Research and Development Program of China