Bone metabolism in complex regional pain syndrome
Automated TPBS quantification revealed widespread bone metabolism alterations, common in CRPS and detectable beyond qualitative assessment. Although most serum markers remained unchanged, patients with warm CRPS exhibited unique features, suggesting distinct pathophysiological profiles. Integrating novel image analysis with other biomarkers may enhance diagnostic precision and patient stratification for targeted therapies.
Authors
- Michael Alexander Harnik (ORCID: https://orcid.org/0000-0002-0191-5742)
- Ann‐Kristin Reinhold (ORCID: https://orcid.org/0000-0002-0269-462X)
- Gudrun Kindl (ORCID: https://orcid.org/0000-0001-6351-9473)
- Andreas K. Buck (ORCID: https://orcid.org/0000-0002-6447-0613)
- Heike L. Rittner (ORCID: https://orcid.org/0000-0003-4867-0188)
- Frank Birklein (ORCID: https://orcid.org/0000-0002-6672-4226)
- Ulrich Dischinger (ORCID: https://orcid.org/0009-0008-4885-9355)
- Eva Herrmann (ORCID: https://orcid.org/0000-0002-0662-6675)
- Beate Hartmannsberger (ORCID: https://orcid.org/0009-0002-1300-9349)
- Juliane Becker (ORCID: https://orcid.org/0000-0001-5143-4886)
- Annemarie Sodmann
- Abdelrahman Sawalma (ORCID: https://orcid.org/0009-0009-2314-4529)
- Alexander Brack (ORCID: https://orcid.org/0000-0002-3541-7063)
Institutions
- University of Bern (CH)
- Johannes Gutenberg University Mainz (DE)
- University Hospital of Bern (CH)
- University Medical Center of the Johannes Gutenberg University Mainz (DE)
- Universitätsklinikum Würzburg (DE)
Publication Details
- Journal
- PAIN Reports
- Published
- 2024-11-20
- DOI
- https://doi.org/10.1097/pr9.0000000000001217
- Citations
- 6
- Primary Topic
- Pain Management and Treatment
- Type
- article
- Field-Weighted Citation Impact
- 3.85
Funders
- Deutsche Forschungsgemeinschaft