HER2-Targeted Affibody Molecule 99mTc-ABH2 for Imaging HER2 Expression in Breast Cancer
This study validated 99mTc-ABH2 SPECT/CT as a promising diagnostic tool for precise HER2 assessment. The robust sensitivity for immunohistochemistry (3+) tumors and the visualization of metastases highlight its diagnostic significance, potentially impacting patient outcomes positively.
Authors
- Chao Ren (ORCID: https://orcid.org/0000-0002-5418-3354)
- Hongli Jing (ORCID: https://orcid.org/0000-0002-6309-7431)
- Xi Cao (ORCID: https://orcid.org/0009-0006-0510-6877)
- Jiong Cai (ORCID: https://orcid.org/0000-0002-0185-445X)
- Peipei Wang (ORCID: https://orcid.org/0000-0001-7201-4928)
- Xuefei Wang (ORCID: https://orcid.org/0000-0003-3268-3152)
- Qiang Sun (ORCID: https://orcid.org/0000-0001-7547-1470)
- Xiaona Jin
- Fang Li (ORCID: https://orcid.org/0009-0003-2442-6604)
- Yuwei Zhang (ORCID: https://orcid.org/0009-0008-1016-7361)
Institutions
- Chinese Academy of Medical Sciences & Peking Union Medical College (CN)
- Peking Union Medical College Hospital (CN)
Publication Details
- Journal
- Clinical Nuclear Medicine
- Published
- 2024-11-18
- DOI
- https://doi.org/10.1097/rlu.0000000000005535
- Citations
- 2
- Primary Topic
- Monoclonal and Polyclonal Antibodies Research
- Type
- article
- Field-Weighted Citation Impact
- 0.81