Ceftazidime-avibactam (CAZ-AVI) pharmacokinetics in critically ill patients undergoing continuous venovenous hemodiafiltration (CVVHDF)
These results suggest that the CAZ-AVI dose regimens used in this study can be applicable in critically ill patients undergoing CVVHDF, despite the different shape of the PK profiles observed in this population. Further research with a larger patient cohort is warranted to validate and refine these findings.
Authors
- Harry Paskalis
- Ilias Karaiskos (ORCID: https://orcid.org/0000-0002-2226-0239)
- Irena Loryan (ORCID: https://orcid.org/0000-0002-1557-4416)
- Elisabet I. Nielsen (ORCID: https://orcid.org/0000-0003-0725-214X)
- Helen Giamarellou (ORCID: https://orcid.org/0000-0002-7387-5065)
- Lena E. Friberg (ORCID: https://orcid.org/0000-0002-2979-679X)
- Amaury O’Jeanson
- Konstantinos Ioannidis (ORCID: https://orcid.org/0000-0001-9817-8066)
- Lamprini Galani
- Aghavni Ginosyan
Institutions
- Uppsala University (SE)
- Hygeia Hospital (GR)
Publication Details
- Journal
- International Journal of Antimicrobial Agents
- Published
- 2024-11-23
- DOI
- https://doi.org/10.1016/j.ijantimicag.2024.107394
- Citations
- 5
- Primary Topic
- Antibiotics Pharmacokinetics and Efficacy
- Type
- article
- Field-Weighted Citation Impact
- 2.24
Funders
- Vetenskapsrådet
- H2020 Marie Skłodowska-Curie Actions