Liver transplantation for HBV-related liver disease: Impact of prophylaxis for HBV on HCC recurrence

In Italy, the combination of high-barrier nucleos(t)ide analogues and hepatitis B immunoglobulins remains the most widely used regimen for antiviral prophylaxis following liver transplantation for HBV-related liver disease. Hepatitis B recurrence after liver transplantation is a rare event and not associated with reduced survival. In transplant recipients with hepatocellular carcinoma, HBV recurrence was independently associated with hepatocellular carcinoma recurrence, though this may simply reflect an epiphenomenon without any causal relationship.

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Publication Details

Journal
JHEP Reports
Published
2024-11-23
DOI
https://doi.org/10.1016/j.jhepr.2024.101278
Citations
5
Primary Topic
Hepatitis B Virus Studies
Type
article
Field-Weighted Citation Impact
1.93
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Liver transplantation for HBV-related liver disease: Impact of prophylaxis for HBV on HCC recurrence

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JHEP Reports
Hepatitis B Virus Studies
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article

Liver transplantation for HBV-related liver disease: Impact of prophylaxis for HBV on HCC recurrence

Davide Ghinolfi, Salvatore Piano, Flaminia Ferri, Paolo Angeli, Maria Cristina Morelli, Paolo Grossi, Edoardo G. Giannini, Alberto Zanetto, Patrizia Burra, Gianluca Svegliati‐Baroni, Nicola De Maria, Maria Rendina, Alberto Ferrarese, Duilio Pagano, Francesco Paolo Russo, Silvia Martini, Luciano De Carlis, Maria Francesca Donato, Chiara Manuli, Ilaria Lenci, Pier Giuseppe Vacca, Nicola Passigato, Sara Battistella, L. Pasulo, Francesca Romana Ponziani, Sherrie Bhoori, Vincenzo Mazzaferro, Andrea Lauterio, Pierluigi Toniutto, Paolo De Simone, Bianca Magro, Gabriella Frassanito, Laura Turco, Silvia Trapani, Clara Dibenedetto, Ezio Fornasiere, Laura Mameli, S. Fagiuoli, Raffaella Lionetti, Debora Angrisani, D. Forastiere, G. Scandali, Simona Marenco, Alfonso Galeota Lanza, Marco Biolato, V. Giannelli, Alessio Aghemo
article en
5 citations

Abstract

In Italy, the combination of high-barrier nucleos(t)ide analogues and hepatitis B immunoglobulins remains the most widely used regimen for antiviral prophylaxis following liver transplantation for HBV-related liver disease. Hepatitis B recurrence after liver transplantation is a rare event and not associated with reduced survival. In transplant recipients with hepatocellular carcinoma, HBV recurrence was independently associated with hepatocellular carcinoma recurrence, though this may simply reflect an epiphenomenon without any causal relationship.

JHEP ReportsVol. 7(3)
Università Cattolica del Sacro Cuore (IT), University of Pisa (IT), University of Insubria (IT), University of Rome Tor Vergata (IT), Marche Polytechnic University (IT), Humanitas University (IT), University of Padua (IT), Fondazione IRCCS Ca' Granda Ospedale Maggiore Policlinico (IT), Ospedale Maggiore (IT), Ospedale Antonio Cardarelli (IT), Istituto Nazionale per le Malattie Infettive Lazzaro Spallanzani (IT), Azienda Socio Sanitaria Territoriale Grande Ospedale Metropolitano Niguarda (IT), Azienda Ospedaliera Universitaria Integrata Verona (IT), Azienda Universitaria Ospedaliera Consorziale - Policlinico Bari (IT), Azienda Ospedaliera San Camillo-Forlanini (IT), Fondazione Ricerca Molinette (IT), Ospedale Papa Giovanni XXIII (IT), Azienda Ospedaliero-Universitaria di Modena (IT), Azienda USL di Bologna (IT), Ospedale Santa Maria della Misericordia di Udine (IT), Ospedale Policlinico San Martino (IT), Fondazione IRCCS Istituto Nazionale dei Tumori (IT), IRCCS Humanitas Research Hospital (IT), Azienda Sanitaria Universitaria Integrata di Trieste (IT), Azienda Ospedaliera G. Brotzu (IT), Istituto Mediterraneo per i Trapianti e Terapie ad Alta Specializzazione (IT), University of Milano-Bicocca (IT), University of Genoa (IT), Sapienza University of Rome (IT)
Good health and well-being
Openalex Percentile: Top 13%
Hepatitis B Virus Studies
1.93
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