The interaction of second trimester prenatal maternal inflammation and psychosocial stress on offspring depressive symptoms in adolescence
The interaction of the adverse impacts of maternal daily life stress and higher maternal IL-6 and/or IL-8 levels during the second trimester may contribute significantly to exacerbate depression risk in adolescent offspring. These results have potential implications for multiple targets of future early intervention and prevention research.
Authors
- Ann M. Kring (ORCID: https://orcid.org/0000-0003-4836-8229)
- Piera M. Cirillo (ORCID: https://orcid.org/0000-0003-4571-4544)
- Emily Lipner (ORCID: https://orcid.org/0000-0002-0992-2437)
- Lauren B. Alloy (ORCID: https://orcid.org/0000-0002-5196-2635)
- Madeline Pike (ORCID: https://orcid.org/0000-0003-3961-8417)
- Elizabeth C. Breen (ORCID: https://orcid.org/0000-0001-6046-4999)
- Thomas M. Olino (ORCID: https://orcid.org/0000-0001-5139-8571)
- Barbara A. Cohn (ORCID: https://orcid.org/0000-0002-9912-8447)
- Nickilou Y. Krigbaum (ORCID: https://orcid.org/0000-0001-5034-7991)
- Rachel Furlan
- Lauren M. Ellman (ORCID: https://orcid.org/0009-0006-8852-0829)
Institutions
- University of California, Berkeley (US)
Publication Details
- Journal
- Brain Behavior and Immunity Integrative
- Published
- 2024-11-23
- DOI
- https://doi.org/10.1016/j.bbii.2024.100096
- Primary Topic
- Maternal Mental Health During Pregnancy and Postpartum
- Type
- article
- Field-Weighted Citation Impact
- 0.00
Funders
- U.S. Department of Health and Human Services
- National Institutes of Health
- National Institute of Mental Health
- Norman Cousins Center for Psychoneuroimmunology
- Eunice Kennedy Shriver National Institute of Child Health and Human Development