IWR-1 attenuates the promotional effect of IL-36γ in a mouse model of psoriasis
Taken together, our findings suggested that inhibition of the Wnt/β-catenin signaling pathway may be useful in the alleviation of IL-36γ-induced psoriasis-like lesions.
Authors
- Xiaofeng Zheng (ORCID: https://orcid.org/0000-0003-2850-7308)
- Hongzhong Jin (ORCID: https://orcid.org/0000-0001-6234-1554)
- Yimeng Gao (ORCID: https://orcid.org/0000-0002-3717-224X)
- Wenming Wang (ORCID: https://orcid.org/0000-0002-0903-3461)
Institutions
- Chinese Academy of Medical Sciences & Peking Union Medical College (CN)
- Peking Union Medical College Hospital (CN)
Publication Details
- Journal
- BMC Immunology
- Published
- 2024-11-23
- DOI
- https://doi.org/10.1186/s12865-024-00669-1
- Citations
- 2
- Primary Topic
- Psoriasis: Treatment and Pathogenesis
- Type
- article
- Field-Weighted Citation Impact
- 0.48
Funders
- Peking Union Medical College Hospital
- National Key Research and Development Program of China