BACE1 Candidates Inhibitors for Alzheimer's Drug Discovery Using the Transformer-Only Decoder

Our research introduces a groundbreaking approach for creating new molecular structures targeting Beta-secretase 1 (BACE1) in Alzheimer's disease treatment. By using a deep learning framework with a pre-trained Transformer model, fine-tuned on a Selfies BACE1 dataset, we enable accurate and meaningful generation of potential therapeutic compounds. This innovative approach streamlines drug discovery and offers a scalable solution for addressing various therapeutic targets.