Inflammation and Microbial Translocation Correlate with Reduced MAIT Cells in People with HIV
Our findings suggest inflammation and microbial translocation in PWH on ART lead to a loss of MAIT cells via impaired IL-7 responsiveness, resulting in further increased microbial translocation and inflammation.
Authors
- Brian Clagett (ORCID: https://orcid.org/0009-0006-4046-125X)
- Angela Ryu (ORCID: https://orcid.org/0009-0001-3347-4814)
- M. J. Freeman
Institutions
- University Hospitals of Cleveland (US)
- Center for Global Health (US)
- Case Western Reserve University (US)
Publication Details
- Journal
- Pathogens and Immunity
- Published
- 2024-11-21
- DOI
- https://doi.org/10.20411/pai.v10i1.746
- Citations
- 2
- Primary Topic
- Immune Cell Function and Interaction
- Type
- article
- Field-Weighted Citation Impact
- 0.48
Funders
- National Institutes of Health